Publications

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FLAVIVIRUS NS1 TRIGGERS TISSUE-SPECIFIC VASCULAR ENDOTHELIAL DYSFUNCTION REFLECTING DISEASE TROPISM.

Puerta-Guardo, H.*, Glasner, D.R.*, Espinosa, D.A., Biering, S.B., Patana, M., Ratnasiri, K., Wang, C., Beatty, P.R., Harris, E. Cell Rep. 2019 Feb 5;26(6):1598-1613.e8. doi: 10.1016/j.celrep.2019.01.036.

Listen to the episode of This Week in Virology, hosted by Dr. Vincent Racaniello of Columbia University, discussing this manuscript on his weekly podcast.

And to read my layperson summary of this paper, click through to the blog post here.

 
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Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components

Glasner, D.R., Ratnasiri, K., Puerta–Guardo, H., Espinosa, D.A., Beatty, P.R., and Harris, E. PLoS Pathog. 2017 Nov 9;13(11):e1006673. doi: 10.1371/journal.ppat.1006673.

Watch the screen capture and listen to the audio from a talk I gave at the 2017 American Society of Tropical Medicine and Hygiene General Meeting.

 

Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability

Puerta–Guardo, H., Glasner, D.R., and Harris, E. 2016. PLoS Pathog. 2016 Jul 14;12(7):e1005738. doi: 10.1371/journal.ppat.1005738.

 

Additional Publications

THE GOOD, THE BAD, AND THE SHOCKING: THE MULTIPLE ROLES OF DENGUE VIRUS NONSTRUCTURAL PROTEIN 1 IN PROTECTION AND PATHOGENESIS.

Glasner, D.R., Puerta–Guardo, H., Beatty, P.R., and Harris, E. 2016. Annu Rev Virol. 2018 Sep 29;5(1):227-253. doi: 10.1146/annurev-virology-101416-041848.

Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement

Schmid, M.A., Glasner, D.R., Shah, S., Michlmayr, D., Kramer, L.D., and Harris, E. PLoS Pathog. 2016 Jun 16;12(6):e1005676. doi: 10.1371/journal.ppat.1005676.

Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination

Beatty, P.R., Killingbeck S., Puerta–Guardo, H., Glasner, D.R., Hopkins, K.C., and Harris, E. 2015. Sci Transl Med. 2015 Sep 9;7(304):304ra141. doi: 10.1126/scitranslmed.aaa3787.

Evaluation of the Broad-Range PCR-Electrospray Ionization Mass Spectrometry (PCR/ESI-MS) System and Virus Microarrays for Virus Detection

Taliaferro, L.P., Galvin, T.A., Ma, H., Shaheduzzaman, S., Williams, D.K., Glasner, D.R., and Khan, A.S. 2014. Viruses. 2014 Apr 25;6(5):1876-96. doi: 10.3390/v6051876. Erratum in: Viruses. 2014 Nov;6(11):4464-5.

Identification of a Novel Rhabdovirus in Spodoptera frugiperda Cell Lines

Ma, H., Galvin, T.A., Glasner, D.R., Shaheduzzaman, S., and Khan, A.S. 2014. J Virol. 2014 Jun;88(12):6576-85. doi: 10.1128/JVI.00780-14.

No Evidence of Xenotropic Murine Leukemia Virus-Related Virus Transmission by Blood Transfusion from Infected Rhesus Macaques

Williams, D.K., Galvin, T.A., Gao, Y., O’Neill, C.M., Glasner, D.R., and Khan, A.S. 2013. J Virol. 2013 Feb;87(4):2278-86. doi: 10.1128/JVI.02326-12.

Optimization of viral profiling approaches reveals strong links between viral and bacterial communities in a eutrophic freshwater lake

Hardbower, D.M., Dolman, J.L., Glasner, D.R., and Williamson, K.E. 2012. AME, 67:59–76. doi: 10.3354/ame01582.